The new inter-disciplinary eclecticism championed by many philosophers of science has generated a heterogeneous family of science studies projects. Philosophers who favor an inter-disciplinary approach face many problems if they are to successfully forge a hybrid science studies that does not violate their integrity as philosophers in particular, they must isolate an intellectual space in which traditional agendas, such as the concern for the clarification of concepts, can hold court. In this paper, I outline what I regard as a new (...) brand of HPS, one that is deeply rooted in the history of the exact science. The virtue of this New HPS, I will submit, is that it furnishes philosophers of science with a fresh perspective from which to carry on philosophy's classic normative mission. (shrink)

Two principal questions are addressed: In De Finibus 3.54 what position does Cicero imagine the talus to fall and lie? How does this talus simile shed light on the problematic relationship between the Stoics’ doctrine of ‘preferred indifferents’ and their definition of the Good as virtue?

This paper starts by juxtaposing the normative ethics in the final part of Parfit's final book, On What Matters, vol. 3, with the normative ethics in his earlier books, Reasons and Persons and On What Matters, vol. 1. The paper then addresses three questions. The first is, where does the reflective-equilibrium methodology that Parfit endorsed in the first volume of On What Matters lead? The second is, is the Act-involving Act Consequentialism that Parfit considers in the final volume of On (...) What Matters as plausible as Rossian deontology? The third is, how is the new argument that Parfit puts forward for Rule Consequentialism supposed to work? (shrink)

Edited proceedings of an interdisciplinary symposium on consciousness held at the University of Cambridge in January 1978. Includes a foreword by Freeman Dyson. Chapter authors: G. Vesey, R.L. Gregory, H.C. Longuet-Higgins, N.K. Humphrey, H.B. Barlow, D.M. MacKay, B.D. Josephson, M. Roth, V.S. Ramachandran, S. Padfield, and (editorial summary only) E. Noakes. A scanned pdf is available from this web site (philpapers.org), while alternative versions more suitable for copying text are available from https://www.repository.cam.ac.uk/handle/1810/245189. -/- Page numbering convention for the pdf version (...) viewed in a pdf viewer is as follows: 'go to page n' accesses the pair of scanned pages 2n and 2n+1. Applicable licence: CC Attribution-NonCommercial-ShareAlike 2.0. (shrink)

In his Principles of Philosophy, Descartes says, Finally, it is so manifest that we possess a free will, capable of giving or withholding its assent, that this truth must be reckoned among the first and most common notions which are born with us.

Fixed-rate versions of rule-consequentialism and rule-utilitarianism evaluate rules in terms of the expected net value of one particular level of social acceptance, but one far enough below 100% social acceptance to make salient the complexities created by partial compliance. Variable-rate versions of rule-consequentialism and rule-utilitarianism instead evaluate rules in terms of their expected net value at all different levels of social acceptance. Brad Hooker has advocated a fixed-rate version. Michael Ridge has argued that the variable-rate version is better. The (...) debate continues here. Of particular interest is the difference between the implications of Hooker's and Ridge's rules about doing good for others. (shrink)

The Protagoras is the touchstone of Socrates’ moral intellectualist stance. The position in a nutshell stipulates that the proper reevaluation of a desire is enough to neutralize it.[1] The implication of this position is that akrasia or weakness of will is not the result of desire (or fear for that matter) overpowering reason but is due to ignorance. -/- Socrates’ eliminativist position on weakness of will, however, flies in the face of the common-sense experience regarding akratic action and thus Aristotle (...) was at pains to render Socrates’ account of moral incontinence intelligible. The key improvement Aristotle makes to Socrates’s model is to underscore that the conditioning of the akratic’s body plays a critical role in determining the power of one’s appetites and, accordingly, the capacity of one to resist the temptations these appetites present for rational evaluation. As Aristotle puts it, “For the incontinent man is like the people who get drunk quickly and on little wine, i.e., on less than most people.” (1151a 3-4). Aristotle presents what I shall call a somatic paradigm (i.e. the drunkard analogy) in order to tackle the problem of akrasia and it is this somatic solution that marks a significant improvement over Socrates’s intellectualist or informational model or so the tradition tells us. -/- In this paper, I wish to push back on the above Aristotelian explanation. I argue that when one fully examines Socrates’ account of weakness of will that Aristotle’s solution is less effective than is traditionally thought. In fact, Socrates can bring Aristotle’s model into his own; just as Aristotle absorbs what is right about Socrates’s model, namely, that akratic action utilizes reason but to a limited degree, Socrates in Meno (77C-78A) develops his own somatic model of weakness of will that connects to the intellectualist paradigm of the Protagoras. To achieve this rapprochement between the two models, I zero in on the description provided by Socrates of those individuals who desire bad things knowing they are bad as “ill-starred” or “bad spirited” (κακοδαίμων ). The “bad-spirited” is the coward and, in contrast to Aristotle’s drunkard, becomes fearful quickly from little danger. This additional somatic component, when connected to Socrates’s position on akrasia in Protagoras adds a new twist to Socrates’s model in the following way: while no one wishes to be ill-starred such that more harm than good will befall one, one may become so as a result of the bad choices one knowingly makes. -/- -/- [1] “After him came Socrates, who spoke better and further about this subject, but even he was not successful. For he used to make the virtues into sciences, and this is impossible. For the sciences all involve reason, and reason is to be found in the intellectual part of the soul. So that all the virtues, according to him arise in the rational part of the soul. The result is that in making the virtues into sciences he is doing away with the nonrational part of the soul and is thereby doing away with passion and character…” (Aristotle, Magna Moralia 1.1. 1182 a15-26). (shrink)

Many writers have held that in his later work, David Lewis adopted a theory of predicate meaning such that the meaning of a predicate is the most natural property that is (mostly) consistent with the way the predicate is used. That orthodox interpretation is shared by both supporters and critics of Lewis's theory of meaning, but it has recently been strongly criticised by Wolfgang Schwarz. In this paper, I accept many of Schwarze's criticisms of the orthodox interpretation, and add some (...) more. But I also argue that the orthodox interpretation has a grain of truth in it, and seeing that helps us appreciate the strength of Lewis's late theory of meaning. (shrink)

Wittgenstein asks: “Now what do the words of this language signify?—What is supposed to shew what they signify, if not the kind of use they have?” Might one answer that rhetorical question by giving a compositional semantics for Wittgenstein’s builder language?

Lankford’s (2013) essential empirical argument, which is based on evidence such as psychological autopsies, is that suicide attacks are caused by suicidality. By operationalizing this causal claim in a hypothetical experiment, I show the claim to be provable, and I contend that its truth is supported by Lankford’s data. However, I question the success of his follow-on arguments about beauty and goodness.

Predictive algorithms are playing an increasingly prominent role in society, being used to predict recidivism, loan repayment, job performance, and so on. With this increasing influence has come an increasing concern with the ways in which they might be unfair or biased against individuals in virtue of their race, gender, or, more generally, their group membership. Many purported criteria of algorithmic fairness concern statistical relationships between the algorithm’s predictions and the actual outcomes, for instance requiring that the rate of false (...) positives be equal across the relevant groups. We might seek to ensure that algorithms satisfy all of these purported fairness criteria. But a series of impossibility results shows that this is impossible, unless base rates are equal across the relevant groups. What are we to make of these pessimistic results? I argue that none of the purported criteria, except for a calibration criterion, are necessary conditions for fairness, on the grounds that they can all be simultaneously violated by a manifestly fair and uniquely optimal predictive algorithm, even when base rates are equal. I conclude with some general reflections on algorithmic fairness. (shrink)

Molyneux’s question, whether the newly sighted might immediately recognize tactilely familiar shapes by sight alone, has produced an array of answers over three centuries of debate and discussion. I propose the first pluralist response: many different answers, both yes and no, are individually sufficient as an answer to the question as a whole. I argue that this is possible if we take the question to be cluster concept of sub-problems. This response opposes traditional answers that isolate specific perceptual features as (...) uniquely applicable to Molyneux’s question and grant viability to only one reply. Answering Molyneux’s question as a cluster concept may also serve as a methodology for resolving other philosophical problems. (shrink)

Hume’s account of causation is often regarded a challenge Kant must overcome if the Critical philosophy is to be successful. But from Kant’s time to the present, Hume’s denial of our ability to cognize supersensible objects, a denial that relies heavily on his account of causation, has also been regarded as a forerunner to Kant’s critique of metaphysics. After identifying reasons for rejecting Wayne Waxman’s recent account of Kant’s debt to Hume, I present my own, more modest account of this (...) debt, an account that seeks to unite the two very different pictures of Kant’s relationship to Hume sketched above. (shrink)

Theories of individual well‐being fall into three main categories: hedonism, the desire‐fulfilment theory, and the list theory (which maintains that there are some things that can benefit a person without increasing the person's pleasure or desire‐fulfilment). The paper briefly explains the answers that hedonism and the desire‐fulfilment theory give to the question of whether being virtuous constitutes a benefit to the agent. Most of the paper is about the list theory's answer.

Eric Watkins has argued on philosophical, textual, and historical grounds that Kant’s account of causation in the first Critique should not be read as an attempt to refute Hume’s account of causation. In this paper, I challenge the arguments for Watkins’ claim. Specifically, I argue (1) that Kant’s philosophical commitments, even on Watkins’ reading, are not obvious obstacles to refuting Hume, (2) that textual evidence from the “Disciple of Pure Reason” suggests Kant conceived of his account of causation as such (...) a refutation, and (3) that none of Hume’s early German critics provided responses to this account that would have satisfied Kant. Watkins’ reading of Kant’s account of causation is thus more compatible with traditional views about Kant’s relationship to Hume than Watkins believes. (shrink)

A recent paper by Tom Stern suggests that Socrates’s philosophical psychology, which emphasizes rational reflection, is superior to Nietzsche’s drive model when explaining human behavior. I argue that Stern’s analysis is wrong on three fronts. First, the models share common, though inverted, features. Second, Stern fails to consider the role of Socrates’s daimon when evaluating Socrates’s philosophy of mind; third, Nietzsche’s model is more warranted. In sum, Nietzsche’s philosophical psychology is a correction of the Socratic.

This paper explores an emerging sub-field of both empirical bioethics and experimental philosophy, which has been called “experimental philosophical bioethics” (bioxphi). As an empirical discipline, bioxphi adopts the methods of experimental moral psychology and cognitive science; it does so to make sense of the eliciting factors and underlying cognitive processes that shape people’s moral judgments, particularly about real-world matters of bioethical concern. Yet, as a normative discipline situated within the broader field of bioethics, it also aims to contribute to substantive (...) ethical questions about what should be done in a given context. What are some of the ways in which this aim has been pursued? In this paper, we employ a case study approach to examine and critically evaluate four strategies from the recent literature by which scholars in bioxphi have leveraged empirical data in the service of normative arguments. (shrink)

A paper of Roger Crisp’s four years ago contained arguments that seemed to imply that having deep personal relationships does not constitute an element of well‐being. The lesson to draw from that paper of Crisp’s, according to a recent journal article of mine, is that one’s having a deep personal relationship does constitute an element of one’s well‐being on condition that one’s affection for the other person is merited. Crisp’s paper earlier in this issue of Ratio responds to my arguments. (...) Here I reply to new questions that Crisp poses or provokes. (shrink)

Recent research has relied on trolley-type sacrificial moral dilemmas to study utilitarian versus nonutili- tarian modes of moral decision-making. This research has generated important insights into people’s attitudes toward instrumental harm—that is, the sacrifice of an individual to save a greater number. But this approach also has serious limitations. Most notably, it ignores the positive, altruistic core of utilitarianism, which is characterized by impartial concern for the well-being of everyone, whether near or far. Here, we develop, refine, and validate a (...) new scale—the Oxford Utilitarianism Scale—to dissociate individual differences in the ‘negative’ (permissive attitude toward instrumental harm) and ‘positive’ (impartial concern for the greater good) dimensions of utilitarian thinking as manifested in the general population. We show that these are two independent dimensions of proto-utilitarian tendencies in the lay population, each exhibiting a distinct psychological profile. Empathic concern, identification with the whole of humanity, and concern for future generations were positively associated with impartial beneficence but negatively associated with instrumental harm; and although instrumental harm was associated with subclinical psychopathy, impartial beneficence was associated with higher religiosity. Importantly, although these two dimensions were independent in the lay population, they were closely associated in a sample of moral philosophers. Acknowledging this dissociation between the instrumental harm and impartial beneficence components of utilitarian thinking in ordinary people can clarify existing debates about the nature of moral psychology and its relation to moral philosophy as well as generate fruitful avenues for further research. (shrink)

In “Now the French are invading England” (Analysis 62, 2002, pp. 34-41), Komarine Romdenh-Romluc offers a new theory of the relationship between recorded indexicals and their content. Romdenh-Romluc’s proposes that Kaplan’s basic idea, that reference is determined by applying a rule to a context, is correct, but we have to be careful about what the context is, since it is not always the context of utterance. A few well known examples illustrate this. The “here” and “now” in “I am not (...) here now” on an answering machine do not refer to the time and place of the original utterance, but to the time the message is played back, and the place its attached telephone is located. Any occurrence of “today” in a newspaper or magazine refers not to the day the story in which it appears was written, nor to the day the newspaper or magazine was printed, but to the cover date of that publication. Still, it is plausible that for each (token of an) indexical there is a salient context, and that “today” refers to the day of its context, “here” to the place of its context, and soon. Romdenh-Romluc takes this to be true, and then makes a proposal about what the salient context is. It is “the context that Ac would identify on the basis of cues that she would reasonably take U to be exploiting.” (39) Ac is the relevant audience, “the individual who it is reasonable to take the speaker to be addressing”, and who is assumed to be linguistically competent and attentive. (So Ac might not be the person U intends to address. This will not matter for what follows.) The proposal seems to suggest that it is impossible to trick a reasonably attentive hearer about what the referent of a particular indexical is. Since such trickery does seem possible, Romdenh-Romluc’s theory needs (at least) supplementation. I present two examples of such tricks. (shrink)

How do people think about the mental states of robots? Experimental philosophers have developed various models aiming to specify the factors that drive people's attributions of mental states to robots. Here we report on a new experiment involving robots, the results of which tell against competing models. We advocate a view on which attributions of mental states to robots are driven by the same dual-process architecture that subserves attributions of mental states more generally. In support of this view, we leverage (...) recent psychological research on human-robot interaction that involve ecologically-valid stimuli such as Roombas and humanoid robots. (shrink)

There is a case to be made for the contention that it is a virtue to have a disposition to try to conform to W. K. Clifford’s ethics of belief. The arguments are not Clifford’s own but new deductive ones. There is also a discussion of some recent criticisms of Clifford. They seldom succeed against Clifford’s original position and never succeed against the case for the Cliffordian virtue. It is pointed out that there need be no conflict between religion and (...) Cliffordianism. The virtue approach emphasizes the value of striving over the value of success. (shrink)

Accuracy‐first epistemology is an approach to formal epistemology which takes accuracy to be a measure of epistemic utility and attempts to vindicate norms of epistemic rationality by showing how conformity with them is beneficial. If accuracy‐first epistemology can actually vindicate any epistemic norms, it must adopt a plausible account of epistemic value. Any such account must avoid the epistemic version of Derek Parfit's “repugnant conclusion.” I argue that the only plausible way of doing so is to say that accurate credences (...) in certain propositions have no, or almost no, epistemic value. I prove that this is incompatible with standard accuracy‐first arguments for probabilism, and argue that there is no way for accuracy‐first epistemology to show that all credences of all agents should be coherent. (shrink)

Sam Berstler has recently argued for a fairness-based moral difference between lying and misleading. According to Berstler, the liar, but not the misleader, unfairly free rides on the Lewisian conventions which ground public-language meaning. Although compelling, the pragmatic and metasemantic backdrop within which this moral reason is located allows for the generation of a vicious explanatory circle. Simply, this backdrop entails that no speaker has ever performed an assertion. As I argue, escaping the circle requires rejecting Berstler’s fairness-based reason against (...) lying. The problem is a general one: the wrong of lying cannot be founded on the goods of language. (shrink)

In his insightful and challenging paper, Jonathan Schaffer argues against a distinction I make in The Ant Trap (Epstein 2015) and related articles. I argue that in addition to the widely discussed “grounding” relation, there is a different kind of metaphysical determination I name “anchoring.” Grounding and anchoring are distinct, and both need to be a part of full explanations of how facts are metaphysically determined. Schaffer argues instead that anchoring is a species of grounding. The crux of his argument (...) comes in the last sections of his paper, in his discussion of “exportation,” the relations strategy, and the definitions strategy. I am inclined to agree that Schaffer’s interesting strategies offer the best choices for the philosopher who wants to insist that anchoring is a species of grounding. But both, I will argue, are fatally flawed. I do not take the separation of anchors from grounds lightly, but find the evidence in its favor overwhelming. And once the distinction is made, I find anchoring to be a powerful practical tool in metaphysics. Philosophy and Phenomenological Research, Volume 99, Issue 3, Page 768-781, November 2019. (shrink)

Review and response to Gimbel’s Isn’t That Clever.

Moral realism faces a well known genealogical debunking challenge. I argue that the moral realist’s best response may involve abandoning metaphysical naturalism in favor of some form of axiarchism—the view, very roughly, that the natural world is “ordered to the good.” Axiarchism comes in both theistic and non-theistic forms, but all forms agree that the natural world exists and has certain basic features because it is good for it to exist and have those features. I argue that theistic and non-theistic (...) forms of axiarchism are better positioned than metaphysical naturalism to avoid two commitments that a moral realist should seek to avoid: that the correctness of our moral beliefs is a major coincidence, and that there is a complete explanation of our moral beliefs that does not mention any moral truths. (shrink)

The foundational principles of representative democracy are under attack globally. What we desperately need are enlightened and persuasive public intellectuals who can help us see through the fog of our fear, anger, and disillusionment, to find our rational political commitments again. One of these public intellectuals is undoubtedly Yuval Noah Harari, the bestselling author of three recent books – Sapiens, Homo Deus, and 21 Lessons for the 21st Century. Harari is also a frequent contributor in the popular press, and a (...) guest on shows, podcasts, panels, and as a keynote speaker. Add to all this that Harari is acting on his lofty academic ideals through ‘Sapienship’, a multidisciplinary organization he cofounded that advocates for global responsibility, clarifies the global conversation, and focuses attention on the most important global challenges. I single out Harari because I presume many readers will be familiar with his work. He is certainly one of the fastest rising stars of public intellectualism. Unfortunately, his work is undercut by the philosophical positions he put forth in his first bestselling book, Sapiens. In this review/critique I wish to show that in order for Harari advance a coherent political or ideological argument, he must first shore up his philosophical commitments. (shrink)

Pharmaceuticals or other emerging technologies could be used to enhance (or diminish) feelings of lust, attraction, and attachment in adult romantic partnerships. While such interventions could conceivably be used to promote individual (and couple) well-being, their widespread development and/or adoption might lead to “medicalization” of human love and heartache—for some, a source of serious concern. In this essay, we argue that the “medicalization of love” need not necessarily be problematic, on balance, but could plausibly be expected to have either good (...) or bad consequences depending upon how it unfolds. By anticipating some of the specific ways in which these technologies could yield unwanted outcomes, bioethicists and others can help direct the course of love’s “medicalization”—should it happen to occur—more toward the “good” side than the “bad.”. (shrink)

The work of Richard H. Popkin both introduced the concept of skeptical fideism and served to impressively document its importance in the philosophies of a diverse range of thinkers, including Montaigne, Pascal, Huet, and Bayle. Popkin’s landmark History of Scepticism, however, begins its coverage with the Renaissance. In this paper I explore the roots of skeptical fideism in ancient Greek and Roman philosophy, with special attention to Cicero’s De Natura Deorum, the oldest surviving text to clearly develop a skeptical fideist (...) perspective. (shrink)

Humean supervenience is the conjunction of three theses: Truth supervenes on being, Anti‐haecceitism, and Spatiotemporalism. The first clause is a core part of Lewis's metaphysics. The second clause is related to Lewis's counterpart theory. The third clause says there are no fundamental relations beyond the spatiotemporal, or fundamental properties of extended objects. Supervenience is classified into strong modal Humean supervenience, local modal Humean supervenience and familiar modal Humean supervenience which states that: for any two "worlds like ours", if the spatiotemporal (...) distribution of fundamental qualities is the same at each world, the contingent facts are also the same. The fact that quantum mechanics raises problems for Humean supervenience does not undercut the philosophical significance of Lewis's defense of Humean supervenience. Humean supervenience says that in a world like ours, the fundamental properties are local qualities: perfectly natural intrinsic properties of points, or of point‐sized occupants of points. (shrink)

In this paper I argue that there is a difficulty for Fine's exact semantics for counterfactuals. The difficulty undermines Fine's reasons for preferring exact semantics to possible worlds semantics.

Derek Parfit’s On What Matters endorses Kantian Contractualism, the normative theory that everyone ought to follow the rules that everyone could rationally will that everyone accept. This paper explores Parfit’s argument that Kantian Contractualism converges with Rule Consequentialism. A pivotal concept in Parfit’s argument is the concept of impartiality, which he seems to equate agent-neutrality. This paper argues that equating impartiality and agent-neutrality is insufficient, since some agent-neutral considerations are silly and some are not impartial. Perhaps more importantly, there is (...) little realistic prospect of Kantian Contractualism converging with Rule Consequentialism unless the same impartial reasons drive rule selection in the two theories. (shrink)

Uncertainty plays an important role in The General Theory, particularly in the theory of interest rates. Keynes did not provide a theory of uncertainty, but he did make some enlightening remarks about the direction he thought such a theory should take. I argue that some modern innovations in the theory of probability allow us to build a theory which captures these Keynesian insights. If this is the right theory, however, uncertainty cannot carry its weight in Keynes’s arguments. This does not (...) mean that the conclusions of these arguments are necessarily mistaken; in their best formulation they may succeed with merely an appeal to risk. (shrink)

A common argument for favouring Evidential Decision Theory (EDT) over Causal Decision Theory (CDT) is that EDT has predictably higher expected returns in Newcomb Problems. But this doesn’t show much. For almost any pair of theories you can come up with cases where one does, on average, better than the other. Here I describe a case involving dynamic choice where EDT predictably does worse than CDT.

The Equal Weight View of disagreement says that if an agent sees that an epistemic peer disagrees with her about p, the agent should change her credence in p to half way between her initial credence, and the peer’s credence. But it is hard to believe the Equal Weight View for a surprising reason; not everyone believes it. And that means that if one did believe it, one would be required to lower one’s belief in it in light of this (...) peer disagreement. Brian Weatherson explores the options for how a proponent of the Equal Weight View might respond to this difficulty, and how this challenge fits into broader arguments against the Equal Weight View. (shrink)

One's inaccuracy for a proposition is defined as the squared difference between the truth value (1 or 0) of the proposition and the credence (or subjective probability, or degree of belief) assigned to the proposition. One should have the epistemic goal of minimizing the expected inaccuracies of one's credences. We show that the method of minimizing expected inaccuracy can be used to solve certain probability problems involving information loss and self-locating beliefs (where a self-locating belief of a temporal part of (...) an individual is a belief about where or when that temporal part is located). We analyze the Sleeping Beauty problem, the duplication version of the Sleeping Beauty problem, and various related problems. (shrink)

A concise open-access textbook intended for an undergraduate audience, which brings together essential selections from Gandhi on nonviolence with supplementary materials, including: a preface; boxes providing examples, historical notes, extended explanations, and related philosophical work; overviews of post-Gandhian developments in nonviolence; diagrams, tables, and photos; discussion questions; reading and viewing suggestions; and a glossary.

The importance of the pure concepts of the understanding (i.e. the categories) within Kant’s system of philosophy is undeniable. As I hope to make clear in this essay, however, the categories are also an essential part of Kant’s critique of Christian Wolff. In particular, I argue that Kant’s development of the categories represents a decisive break with the Wolffian conception of the understanding and that this break is central to understanding the task of the Transcendental Analytic. This break, however, is (...) not merely that Kant affirms while Wolff and his followers deny a sharp distinction between sensibility and the understanding, which is the aspect of Kant’s rejection of Wolff that scholars most frequently note. Rather, this break concerns differences in their views about the understanding itself. For while Wolff conceives of the understanding as a mental capacity to extract and make distinct content already present in the senses, Kant conceives of the understanding in its “real use” as a capacity to produce purely intellectual content. (shrink)

The current COVID-19 pandemic and the previous SARS/MERS outbreaks of 2003 and 2012 have resulted in a series of major global public health crises. We argue that in the interest of developing effective and safe vaccines and drugs and to better understand coronaviruses and associated disease mechenisms it is necessary to integrate the large and exponentially growing body of heterogeneous coronavirus data. Ontologies play an important role in standard-based knowledge and data representation, integration, sharing, and analysis. Accordingly, we initiated the (...) development of the community-based Coronavirus Infectious Disease Ontology in early 2020. -/- As an Open Biomedical Ontology (OBO) library ontology, CIDO is open source and interoperable with other existing OBO ontologies. CIDO is aligned with the Basic Formal Ontology and Viral Infectious Disease Ontology. CIDO has imported terms from over 30 OBO ontologies. For example, CIDO imports all SARS-CoV-2 protein terms from the Protein Ontology, COVID-19-related phenotype terms from the Human Phenotype Ontology, and over 100 COVID-19 terms for vaccines (both authorized and in clinical trial) from the Vaccine Ontology. CIDO systematically represents variants of SARS-CoV-2 viruses and over 300 amino acid substitutions therein, along with over 300 diagnostic kits and methods. CIDO also describes hundreds of host-coronavirus protein-protein interactions (PPIs) and the drugs that target proteins in these PPIs. CIDO has been used to model COVID-19 related phenomena in areas such as epidemiology. The scope of CIDO was evaluated by visual analysis supported by a summarization network method. CIDO has been used in various applications such as term standardization, inference, natural language processing (NLP) and clinical data integration. We have applied the amino acid variant knowledge present in CIDO to analyze differences between SARS-CoV-2 Delta and Omicron variants. CIDO's integrative host-coronavirus PPIs and drug-target knowledge has also been used to support drug repurposing for COVID-19 treatment. -/- CIDO represents entities and relations in the domain of coronavirus diseases with a special focus on COVID-19. It supports shared knowledge representation, data and metadata standardization and integration, and has been used in a range of applications. (shrink)

In “A Reliabilist Solution to the Problem of Promiscuous Bootstrapping”, Hilary Kornblith (2009) proposes a reliabilist solution to the bootstrapping problem. I’m going to argue that Kornblith’s proposal, far from solving the bootstrapping problem, in fact makes the problem much harder for the reliabilist to solve. Indeed, I’m going to argue that Kornblith’s considerations give us a way to develop a quick reductio of a certain kind of reliabilism. Let’s start with a crude statement of the problem. The bootstrapper, call (...) them S, looks at a device D1 that happens to be reliable, though at this stage S doesn’t know this. We assume that S is a reliable reader of devices. S then draws the following conclusions. (shrink)

Enneads I: 8.14 poses significant problems for scholars working in the Plotinian secondary literature. In that passage, Plotinus gives the impression that the body and not the soul is causally responsible for vice. The difficulty is that in many other sections of the same text, Plotinus makes it abundantly clear that the body, as matter, is a mere privation of being and therefore represents the lowest rung on the proverbial metaphysical ladder. A crucial aspect to Plotinus’s emanationism, however, is that (...) lower levels of a metaphysical hierarchy cannot causally influence higher ones and, thus, there is an inconsistency in the Egyptian’s magnum opus, or so it would seem. Scholars have sought to work through this paradox by positing that Plotinus is a “paleolithic Platonist” or Socratic. The advantage of this approach is that one may be able to resolve the tension by invoking Socrates’s eliminativist solution to the problem of weakness of will, as found in The Protagoras. In the following article, I argue that such attempts are not wrong-headed just underdetermined. They take up the standard reading of Socratic moral intellectualism, namely the “informational” interpretation and, therefore, fail to render a coherent view of Plotinus’s moral philosophy. The following paper, in contrast, utilizes a new reading of intellectualism advanced by Brickhouse and Smith, which, when subtended with a “powers approach” to causality, resolves the aforementioned, problematic passage of Enneads. (shrink)

It is often claimed that the structure of the Transcendental Logic is modeled on the Wolffian division of logic textbooks into sections on concepts, judgments, and inferences. While it is undeniable that the Transcendental Logic contains elements that are similar to the content of these sections, I believe these similarities are largely incidental to the structure of the Transcendental Logic. In this essay, I offer an alternative and, I believe, more plausible account of Wolff’s influence on the structure of the (...) Transcendental Logic, one that puts the focus on his empirical psychology rather than his logic. In particular, I argue that the structure of the Transcendental Logic is deeply indebted to a conception of purity that Wolff introduces in his empirical psychology and that this conception sheds more light on the overall structure of the Transcendental Logic than the accepted view. In section one, I outline two conceptions of purity found in Kant and trace them to similar views in Wolff. In section two, I turn to Kant’s views about logic as they are expressed in the Critique and argue that it is best to interpret Kant’s taxonomy of logic on its own terms rather than reading it through its terminological similarities to aspects of the Wolffian tradition. In section three, I argue that the second of the two conceptions of purity identified in section one is central to the structure of the Transcendental Logic. In doing so, I argue against the widespread view that this section of the Critique is modeled solely on what Kant calls pure general logic as opposed to both pure and applied general logic. I then conclude by briefly reviewing my account and considering some of its broader implications for our understanding of Kant. (shrink)

Kaplan (1989) famously claimed that monsters--operators that shift the context--do not exist in English and "could not be added to it". Several recent theorists have pointed out a range of data that seem to refute Kaplan's claim, but others (most explicitly Stalnaker 2014) have offered a principled argument that monsters are impossible. This paper interprets and resolves the dispute. Contra appearances, this is no dry, technical matter: it cuts to the heart of a deep disagreement about the fundamental structure of (...) a semantic theory. We argue that: (i) the interesting notion of a monster is not an operator that shifts some formal parameter, but rather an operator that shifts parameters that play a certain theoretical role; (ii) one cannot determine whether a given semantic theory allows monsters simply by looking at the formal semantics; (iii) theories which forbid shifting the formal "context" parameter are perfectly compatible with the existence of monsters (in the interesting sense). We explain and defend these claims by contrasting two kinds of semantic theory--Kaplan's (1989) and Lewis's (1980). (shrink)

I defend interest-relative invariantism from a number of recent attacks. One common thread to my response is that interest-relative invariantism is a muchweaker thesis than is often acknowledged, and a number of the attacks only challenge very specific, and I think implausible, versions of it. Another is that a number of the attacks fail to acknowledge how many things we have independent reason to believe knowledge is sensitive to. Whether there is a defeater for someone's knowledge can be sensitive to (...) all manner of features of their environment, as the host of examples from the post-Gettier literature shows. Adding in interest-sensitive defeaters is a much less radical move than most critics claim it is. (shrink)